Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754853 | 0.80 | KDM4E (0.34) | POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14754842 | 0.76 | POLB (0.39) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL22330359 | 0.75 | MEN1 (0.42) | MEN1KMT2APOLBHSD11B1MAPK1 | |
| SCHEMBL22330447 | 0.74 | MEN1 (0.41) | MEN1KMT2APOLBLMNAHSD11B1 | |
| SCHEMBL13377049 | 0.73 | SMN1; SMN2 (0.45) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL16739869 | 0.73 | MEN1 (0.36) | MEN1KMT2ALMNAHSD11B1 | |
| SCHEMBL13377083 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL22166766 | 0.71 | POLB (0.39) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL27392383 | 0.70 | POLB (0.38) | POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29876882 | 0.70 | MEN1 (0.40) | MEN1KMT2APOLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154683-A1 | METHODS OF TREATING DISEASE WITH MAGL INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2020-07-30 | — | — | WO | disclosed |