SCHEMBL22273624

SCHEMBL22273624

O=c1ccc2cc(OI)c(O)cc2o1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.71
ALDH1A1 P00352 6/20 0.71
HPGD P15428 6/20 0.71
CASP1 P29466 6/20 0.71
CASP7 P55210 6/20 0.71
CA9 Q16790 5/20 0.71
HSD17B10 Q99714 5/20 0.71
MCL1 Q07820 4/20 0.71
CA12 O43570 4/20 0.71
GLA P06280 4/20 0.71
GAA P10253 4/20 0.71
AKR1B1 P15121 3/20 0.71
CYP1A2 P05177 2/20 0.71
HIF1A Q16665 2/20 0.71
ERAP1 Q9NZ08 2/20 0.71
CA1 P00915 2/20 0.71
CA7 P43166 2/20 0.71
CA13 Q8N1Q1 2/20 0.71
MEN1 O00255 2/20 0.71
AMY1A P0DUB6 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Scopoletin SCHEMBL29712325 0.83 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
Scopoletin SCHEMBL147702 0.83 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
Scopoletin SCHEMBL21114360 0.83 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
SCHEMBL7795064 0.81 CA9 (0.68) KDM4EALDH1A1HPGDCASP1CASP7
Scopoletin SCHEMBL5060518 0.81 CA9 (0.94) KDM4EALDH1A1HPGDCASP1CASP7
Esculetin SCHEMBL6867015 0.80 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
Esculetin SCHEMBL29569228 0.80 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
Esculetin SCHEMBL24641 0.80 CA9 (1.00) KDM4EALDH1A1HPGDCASP1CASP7
SCHEMBL8808225 0.80 CA9 (0.70) KDM4EALDH1A1HPGDCASP1CASP7
SCHEMBL31689335 0.80 KDM4E (0.72) KDM4EALDH1A1HPGDCASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020153608-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GOUT COMPRISING MORINDA CITRIFOLIA EXTRACT OR SCOPOLETIN ISOLATED THEREFROM AS AN ACTIVE INGREDIENT WELLNESSBIO INC. (KR) 2020-07-30 WO disclosed