Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | CA12 | O43570 | 7/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | CASP1 | P29466 | 4/20 | 1.00 |
| ▸ | CASP7 | P55210 | 4/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Esculetin SCHEMBL6867015 | 1.00 | CA9 (1.00) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL29569228 | 1.00 | CA9 (1.00) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL29163498 | 0.98 | CA9 (0.96) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL1736697 | 0.98 | CA9 (0.96) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL8708221 | 0.98 | CA9 (0.96) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL30120615 | 0.98 | CA9 (0.96) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL6703123 | 0.92 | CA9 (0.85) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL8716360 | 0.91 | CA9 (0.82) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL8528963 | 0.91 | CA9 (0.82) | CA9CA12MCL1GAAKDM4E | |
| Esculetin SCHEMBL8718947 | 0.89 | CA9 (0.79) | CA9CA12MCL1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7734 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629336-B2 | Compositions and methods of use thereof for treatment of mastitis | CUREMAST, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036666-A | Method for extracting aesculetin and application of aesculetin in plant disease control | 西南大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122010154-A | Method for preparing high-whiteness cubic nano calcium carbonate at low temperature | 湖北三峡实验室 | 2026-05-12 | — | — | CN | claimed |
| WO-2025217103-A1 | DURABLE ION EXCHANGE MEMBRANES WITH ADDITIVES | W. L. GORE & ASSOCIATES, INC. (US) | 2025-10-16 | — | — | WO | claimed |
| US-20250304851-A1 | METHODS AND COMPOSITIONS USED IN CONTROLLING FORMATION SAND PRODUCTION, PROPPANT FLOWBACK, AND FINES MIGRATION | HALLIBURTON ENERGY SERVICES, INC | 2025-10-02 | — | — | US | claimed |
| US-12421419-B2 | Preparation method for ultraviolet-responsive coumarin controlled-release and self-repairing anti-fouling paint | Quzhou Research Institute of Zhejiang University (CN) | 2025-09-23 | — | — | US | claimed |
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | claimed |
| CN-120131676-A | Tablet containing risedronate sodium and application thereof | 天津市中西医结合医院（天津市南开医院） | 2025-06-13 | — | — | CN | claimed |
| CN-1132755-A | Aescinic lactonic derivative, its prep. and medicine composition thereof | KUREHA CHEMICAL IND CO LTD (JP) | 1996-10-09 | — | — | CN | claimed |
| EP-0719770-A1 | Esculetin derivatives, method for manufacture thereof, and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1996-07-03 | — | — | EP | claimed |
| WO-1996013158-A2 | PROLONGED PRESERVATION OF BLOOD PLATELETS | LIFECELL CORPORATION (US) | 1996-05-09 | — | — | WO | claimed |
| EP-0694305-A1 | Pharmaceutical or cosmetic formulations containing coumarins and proanthocyanidinis | INDENA S.p.A. (IT) | 1996-01-31 | — | — | EP | claimed |
| EP-0693278-A2 | Combinations of vasoactive substances with fatty acids to prevent hair loss | INDENA S.p.A. (IT) | 1996-01-24 | — | — | EP | claimed |
| WO-1995028098-A1 | TOBACCO PRODUCTS, OR SUBSTANCES SIMILAR TO SUCH PRODUCTS, CONTAINING NATURAL SUBSTANCES WITH ANTI-OXIDANT PROPERTIES, AND PROCESS FOR PRODUCING THE SAME | H.F. & PH.F. REEMTSMA GMBH & CO. (DE) | 1995-10-26 | — | — | WO | claimed |
| US-5455268-A | Treating arthropathy | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-10-03 | — | — | US | claimed |
| CN-1106398-A | Esculetin derivatives, process for manufacture and use thereof, and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 1995-08-09 | — | — | CN | claimed |
| US-4334020-A | Method of producing L-glutamic acid by fermentation | AJINOMOTO COMPANY INCORPORATED (JP) | 1982-06-08 | — | — | US | claimed |
| US-4308348-A | SALMONELLA, SERRATIA, PROTEUS, PROVIDENCIA | LABORATOIRE DE RECHERCHE API (FR) | 1981-12-29 | — | — | US | claimed |