SCHEMBL222749

SCHEMBL222749

CCCc1cc(Cc2cc(C)cc(Cc3cc(CCC)cc(C(C)(C)C)c3O)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 5/20 0.71
CYP2C9 P11712 4/20 0.71
CYP2C19 P33261 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
HSPA5 P11021 2/20 0.68
CYP2D6 P10635 2/20 0.59
HSD17B10 Q99714 1/20 0.59
ALDH1A1 P00352 6/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.46
TYR P14679 1/20 0.46
GAA P10253 3/20 0.43
KMT2A Q03164 3/20 0.43
AMY1A P0DUB6 1/20 0.42
TSHR P16473 3/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 3/20 0.38
MEN1 O00255 2/20 0.38
TP53 P04637 2/20 0.38
CYP1A2 P05177 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138594 0.92 HSPA5 (0.74) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL29976141 0.92 HSPA5 (0.74) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL8070387 0.84 HSPA5 (0.84) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL1615304 0.84 CYP2C9 (0.81) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL7171512 0.84 HSPA5 (0.84) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL29357108 0.84 CYP2C9 (1.00) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL11247674 0.84 CYP2C9 (1.00) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL39149 0.84 CYP2C9 (1.00) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL1576633 0.83 HSPA5 (0.70) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5
SCHEMBL11568213 0.82 HIF1A (0.77) HIF1ACYP2C9CYP2C19SMN1; SMN2HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011855-A1 Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011867-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Outer Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed