SCHEMBL29976141

SCHEMBL29976141

CCCc1cc(Cc2cc(CCC)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.74
HIF1A Q16665 4/20 0.56
CYP2C9 P11712 3/20 0.56
CYP2C19 P33261 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CYP2D6 P10635 2/20 0.50
HSD17B10 Q99714 1/20 0.50
GAA P10253 4/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 7/20 0.44
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 3/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
BLM P54132 2/20 0.43
ATM Q13315 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
GMNN O75496 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138594 1.00 HSPA5 (0.74) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL222749 0.92 HIF1A (0.71) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL1576633 0.90 HSPA5 (0.70) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
Acrylic Acid SCHEMBL6449228 0.87 HSPA5 (0.57) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL8509844 0.87 HSPA5 (0.66) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL3812694 0.87 HSPA5 (0.66) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL3689390 0.87 HSPA5 (0.66) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL3694426 0.87 HSPA5 (0.66) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL3687864 0.87 HSPA5 (0.66) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL163700 0.87 GAA (0.58) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022210295-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME, AND USE APPLICATION FOR SAME 住友化学株式会社 2022-10-06 WO disclosed