Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.46 |
| ▸ | EEF2 | P13639 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | FDPS | P14324 | 13/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230166 | 1.00 | EEF2K (0.46) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2229148 | 1.00 | EEF2K (0.46) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2230206 | 1.00 | EEF2K (0.46) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2228634 | 1.00 | EEF2K (0.46) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2228877 | 0.99 | EEF2K (0.44) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2230997 | 0.94 | EEF2K (0.39) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL2228560 | 0.88 | ACHE (0.37) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL15348252 | 0.88 | ACHE (0.37) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL5287245 | 0.88 | KMT2A (0.55) | EEF2KEEF2MEN1KMT2APLK4 | |
| SCHEMBL1826845 | 0.88 | KMT2A (0.55) | EEF2KEEF2MEN1KMT2APLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730157-B1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |