Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22276148 | 0.87 | TBXA2R (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL23890360 | 0.87 | TBXA2R (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL23890380 | 0.83 | TBXA2R (0.33) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL28484338 | 0.80 | PIK3CA (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276340 | 0.77 | TBXA2R (0.36) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276146 | 0.76 | TBXA2R (0.36) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276149 | 0.75 | TBXA2R (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276338 | 0.73 | PTGER4 (0.39) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276163 | 0.73 | PTGER4 (0.39) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276021 | 0.73 | TBXA2R (0.35) | TBXA2RPTGER1PTGER4PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151566-A1 | COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | 凯复制药有限公司 | 2020-07-30 | — | — | WO | disclosed |