Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22276772 | 0.86 | SRC (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276939 | 0.85 | SRC (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276802 | 0.85 | SRC (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276921 | 0.84 | SRC (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276931 | 0.83 | MEN1 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276774 | 0.83 | HDAC8 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30531814 | 0.82 | SRC (0.75) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276925 | 0.82 | OGT (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL22276934 | 0.82 | PTGS2 (0.50) | SRCHSP90AA1HSP90AB1PTGS2NEU2 | |
| SCHEMBL20341414 | 0.79 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773129-B2 | Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2023-10-03 | — | — | US | disclosed |
| US-20200239512-A1 | METHODS OF PREVENTING OR TREATING ATHEROSCLEROSIS WITH INHIBITORS OF SPECIFIC ISOENZYMES OF HUMAN NEURAMINIDASE | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239512-A1 | METHODS OF PREVENTING OR TREATING ATHEROSCLEROSIS WITH INHIBITORS OF SPECIFIC ISOENZYMES OF HUMAN NEURAMINIDASE | NEU1, NEU3, NEU2 | HDAC3 750/4885HDAC4 1469/4885HDAC1 552/4885 |
| US-11773129-B2 | Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase | NEU1, NEU3, NEU2 | HDAC3 750/4885HDAC4 1469/4885HDAC1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.