Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227222 | 0.91 | GAA (0.57) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL27818229 | 0.86 | GAA (0.85) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL664938 | 0.86 | GAA (0.85) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL2228196 | 0.80 | NPC1 (0.43) | GAAL3MBTL1KMT2AMAPK1LMNA | |
| SCHEMBL7751819 | 0.80 | GAA (0.73) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3668041 | 0.79 | GAA (1.00) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3665477 | 0.78 | GAA (0.71) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL21919785 | 0.78 | GAA (0.71) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3671016 | 0.78 | GAA (0.96) | GAAL3MBTL1MEN1POLBKMT2A | |
| SCHEMBL21104687 | 0.78 | GAA (0.96) | GAAL3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |