Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.96 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665297 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL28091017 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL21104687 | 1.00 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL28720089 | 0.98 | GAA (0.93) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3668041 | 0.98 | GAA (1.00) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL664938 | 0.90 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL27818229 | 0.90 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL7751819 | 0.83 | GAA (0.73) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3665477 | 0.81 | GAA (0.71) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL4153139 | 0.81 | GAA (0.71) | GAAL3MBTL1EPHX1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101970394-A | Novel cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA AS | 2011-02-09 | — | — | CN | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | claimed |
| CN-117343047-A | Bimetal synergistic promotion system and application thereof in asymmetric synthesis of (R, S) -TBAJ-876 | 上海交通大学 | 2024-01-05 | — | — | CN | disclosed |
| EP-4245756-A1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20210340331-A1 | POLYAMINOBORANES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2021-11-04 | — | — | US | disclosed |
| US-11091593-B2 | Polyaminoboranes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-08-17 | — | — | US | disclosed |
| WO-2018138384-A1 | POLYAMINOBORANES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-08-02 | — | — | WO | disclosed |
| CN-105873927-B | 4-azaindole derivatives | 卫材R&D管理有限公司 | 2017-11-28 | — | — | CN | disclosed |
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | disclosed |
| CN-101970394-B | Novel cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA AS | 2015-05-27 | — | — | CN | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| WO-2013153408-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
| CN-101970394-A | Novel cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA AS | 2011-02-09 | — | — | CN | disclosed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | ARNT, AHR, CYP27A1 | GAA 1308/4885L3MBTL1 4065/4885EPHX1 320/4885 |
| US-20150073165-A1 | CATALYST COMPOUNDS | NQO1, IDH2, IDH3B | GAA 3286/4885L3MBTL1 4548/4885EPHX1 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.