Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012158 | 1.00 | HPGD (0.44) | HPGDSMN1; SMN2GAAPKMGLA | |
| SCHEMBL16769030 | 0.91 | HPGD (0.46) | HPGDSMN1; SMN2GAAGLAPOLB | |
| SCHEMBL16769029 | 0.91 | HPGD (0.46) | HPGDSMN1; SMN2GAAGLAPOLB | |
| SCHEMBL21609892 | 0.90 | HPGD (0.47) | HPGDSMN1; SMN2GAAGLAPOLB | |
| SCHEMBL20017218 | 0.89 | SCN9A (0.39) | HPGDPOLBMEN1RAB9AKMT2A | |
| SCHEMBL9562690 | 0.88 | HPGD (0.43) | HPGDSMN1; SMN2GAAGLAPOLB | |
| SCHEMBL9562686 | 0.88 | HPGD (0.43) | HPGDSMN1; SMN2GAAGLAPOLB | |
| SCHEMBL12742052 | 0.88 | HPGD (0.43) | HPGDSMN1; SMN2GAAPKMGLA | |
| SCHEMBL12737163 | 0.88 | HPGD (0.43) | HPGDSMN1; SMN2GAAPKMGLA | |
| SCHEMBL172319 | 0.86 | POLB (0.42) | HPGDSMN1; SMN2GAAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |