Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562690 | 1.00 | HPGD (0.43) | HPGDSMN1; SMN2GLAPOLBGAA | |
| SCHEMBL9562353 | 0.96 | HPGD (0.46) | HPGDSMN1; SMN2GLAPOLBGAA | |
| SCHEMBL9562350 | 0.96 | HPGD (0.46) | HPGDSMN1; SMN2GLAPOLBGAA | |
| SCHEMBL9562420 | 0.91 | HPGD (0.37) | HPGDSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9562414 | 0.91 | HPGD (0.37) | HPGDSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9406403 | 0.91 | KMT2A (0.42) | HPGDSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9406407 | 0.91 | KMT2A (0.42) | HPGDSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9562606 | 0.90 | NPC1 (0.38) | HPGDSMN1; SMN2POLBGAAMEN1 | |
| SCHEMBL9562602 | 0.90 | NPC1 (0.38) | HPGDSMN1; SMN2POLBGAAMEN1 | |
| SCHEMBL7910499 | 0.90 | HPGD (0.42) | HPGDSMN1; SMN2GLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | claimed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0373186-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK PATENT GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| WO-1989008637-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |