Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277535 | 1.00 | GPR119 (0.36) | GPR119HCRTR2CYP2C9ALDH1A1MAPT | |
| SCHEMBL22277503 | 1.00 | GPR119 (0.36) | GPR119HCRTR2CYP2C9ALDH1A1MAPT | |
| SCHEMBL14922675 | 0.94 | GPR119 (0.39) | GPR119HCRTR2SCN9A | |
| SCHEMBL26209565 | 0.94 | GPR119 (0.39) | GPR119HCRTR2SCN9A | |
| SCHEMBL14922621 | 0.94 | GPR119 (0.39) | GPR119HCRTR2SCN9A | |
| SCHEMBL22277365 | 0.92 | GPR119 (0.35) | GPR119HCRTR2MAPT | |
| SCHEMBL22277172 | 0.92 | GPR119 (0.35) | GPR119HCRTR2MAPT | |
| SCHEMBL4400193 | 0.92 | CYP2C9 (0.35) | CYP2C9ALDH1A1MAPTHTT | |
| SCHEMBL15203882 | 0.92 | CYP2C9 (0.35) | CYP2C9ALDH1A1MAPTHTT | |
| SCHEMBL1311026 | 0.92 | CYP2C9 (0.35) | CYP2C9ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |