SCHEMBL222774

SCHEMBL222774

CCOC(CC)=C(C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SOAT1 P35610 1/20 0.44
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
TRPA1 O75762 1/20 0.36
GLO1 Q04760 1/20 0.35
PKM P14618 2/20 0.35
KDM4E B2RXH2 1/20 0.35
FFAR3 O14843 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 2/20 0.34
CYP2D6 P10635 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126032 1.00 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10SOAT1ALOX15
SCHEMBL10602554 0.92 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10SOAT1ALOX15
SCHEMBL5166175 0.84 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10SOAT1HCAR2
SCHEMBL18271564 0.83 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10SOAT1ALOX15
SCHEMBL27504478 0.82 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10SOAT1FFAR3
SCHEMBL5616300 0.82 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10SOAT1ALOX15
SCHEMBL5164512 0.82 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10SOAT1ALOX15
SCHEMBL5167065 0.82 HCAR2 (0.41) ALDH1A1LMNAHSD17B10SOAT1GAA
SCHEMBL7758324 0.82 HCAR2 (0.41) ALDH1A1LMNAHSD17B10SOAT1GAA
SCHEMBL1260993 0.81 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10SOAT1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083844-A1 INTRAOCULAR LENS Benz Research and Development Corporation (US) 2001-03-21 EP claimed
WO-1999056672-A1 INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) 1999-11-11 WO claimed
EP-4577155-A1 STERILE, MOIST PACKAGE AND PACKAGING METHOD FOR HYDROPHOBIC INTRAOCULAR LENS Hanita Lenses Ltd. (IL) 2025-07-02 EP disclosed
WO-2024042519-A9 STERILE, MOIST PACKAGE AND PACKAGING METHOD FOR HYDROPHOBIC INTRAOCULAR LENS HANITA LENSES LTD (IL) 2024-04-11 WO disclosed
WO-2024042519-A1 STERILE, MOIST PACKAGE AND PACKAGING METHOD FOR HYDROPHOBIC INTRAOCULAR LENS HANITA LENSES LTD (IL) 2024-02-29 WO disclosed
US-20180298011-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2018-10-18 US disclosed
EP-3012258-B1 PHARMACEUTICAL COMPOSITION COMPRISING A PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVE AS AN ANTIVIRAL AGENT GILEAD SCIENCES INC (US) 2018-09-19 EP disclosed
US-9957275-B2 Pyrazolo[1,5-A]pyrimidines for antiviral treatment GILEAD SCIENCES, INC. (US) 2018-05-01 US disclosed
US-20170362244-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2017-12-21 US disclosed
EP-2794611-B1 PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS GILEAD SCIENCES INC (US) 2017-10-11 EP disclosed
US-20170190708-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2017-07-06 US disclosed
EP-1083844-B1 INTRAOCULAR LENS BENZ RES & DEV CORP (US) 2004-06-16 EP disclosed
EP-1083844-A1 INTRAOCULAR LENS Benz Research and Development Corporation (US) 2001-03-21 EP disclosed
WO-1999056672-A1 INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) 1999-11-11 WO disclosed
EP-0669356-A1 Aqueous polyurethane resin dispersion, its preparation and the appropriate polyurethane macromers, and their use in aqueous coatings Herberts Gesellschaft mit beschränkter Haftung (DE) 1995-08-30 EP disclosed
US-5378291-A Hexavalent chromium ions, acrylic emulsion polymer NIHON PARKERIZING CO., LTD. (JP) 1995-01-03 US disclosed
US-5272771-A Gloves SMITH & NEPHEW PLC (GB) 1993-12-28 US disclosed
WO-1993021274-A1 MULTILAYER CORE-SHELL POLYMER COMPOSITIONS AS TOUGHENER FOR THERMOSETS AND THERMOPLASTICS THE B.F. GOODRICH COMPANY (US) 1993-10-28 WO disclosed
US-5011275-A Contact lenses, bandages CIBA-GEIGY CORPORATION (US) 1991-04-30 US disclosed
US-4954587-A CONTACT LENSES CIBA-GEIGY CORPORATION (US) 1990-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362244-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT TYMP, ZC3HAV1, TYMS ALDH1A1 1823/4885LMNA 3626/4885HSD17B10 3384/4885
US-20170190708-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT TYMP, ZC3HAV1, TYMS ALDH1A1 1823/4885LMNA 3626/4885HSD17B10 3384/4885
US-20180298011-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT TYMP, ZC3HAV1, TYMS ALDH1A1 1823/4885LMNA 3626/4885HSD17B10 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.