Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277221 | 0.96 | CNR2 (0.39) | CNR2GABRA1GABRB2CNR1FFAR4 | |
| SCHEMBL22277653 | 0.92 | CNR2 (0.38) | CNR2GABRA1GABRB2CNR1FFAR4 | |
| SCHEMBL22277428 | 0.92 | FFAR4 (0.40) | GABRA1GABRB2FFAR4 | |
| SCHEMBL22277522 | 0.90 | FFAR4 (0.37) | CNR2GABRA1GABRB2FFAR4S1PR1 | |
| SCHEMBL22277546 | 0.90 | FFAR4 (0.33) | CNR2GABRA1GABRB2FFAR4S1PR1 | |
| SCHEMBL22277465 | 0.89 | CNR2 (0.37) | CNR2GABRA1GABRB2CNR1FFAR4 | |
| SCHEMBL22277563 | 0.89 | CNR2 (0.34) | CNR2GABRA1GABRB2CNR1FFAR4 | |
| SCHEMBL22277578 | 0.88 | CNR2 (0.39) | CNR2GABRA1GABRB2CNR1FFAR4 | |
| SCHEMBL22277420 | 0.88 | FFAR4 (0.41) | GABRA1GABRB2FFAR4 | |
| SCHEMBL8963123 | 0.88 | CNR2 (0.33) | CNR2GABRA1GABRB2CNR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |