SCHEMBL22277653

SCHEMBL22277653

C=CC1CCC(C2CCC(CCc3ccc(-c4ccc(OCCCC)c(F)c4F)cc3)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.38
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
CNR1 P21554 1/20 0.36
FFAR4 Q5NUL3 3/20 0.34
S1PR1 P21453 4/20 0.33
S1PR3 Q99500 2/20 0.31
PPARG P37231 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277578 0.96 CNR2 (0.39) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL22277471 0.92 CNR2 (0.38) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL22161979 0.92 FFAR4 (0.40) GABRA1GABRB2FFAR4
SCHEMBL22277522 0.90 FFAR4 (0.37) CNR2GABRA1GABRB2FFAR4S1PR1
SCHEMBL22277221 0.88 CNR2 (0.39) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL22269639 0.88 FFAR4 (0.41) GABRA1GABRB2FFAR4
SCHEMBL22277216 0.86 CNR2 (0.35) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL22277546 0.86 FFAR4 (0.33) CNR2GABRA1GABRB2FFAR4S1PR1
SCHEMBL22277468 0.86 S1PR1 (0.39) CNR2GABRA1GABRB2FFAR4S1PR1
SCHEMBL22277542 0.85 FFAR4 (0.41) FFAR4S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed