SCHEMBL22277658

SCHEMBL22277658

C=CCCc1ccc(C2CCC(C3CCC(CCc4ccc(OCC)c(F)c4F)CC3)CC2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.32
SPHK1 Q9NYA1 2/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277325 0.94 FFAR4 (0.33) CYP2C9SPHK1AOC3
SCHEMBL22277614 0.93 SPHK1 (0.35) CYP2C9SPHK1
SCHEMBL22277694 0.90 KDM1A (0.33) CYP2C9
SCHEMBL22277621 0.89 AOC3 (0.32) SPHK1AOC3
SCHEMBL22277588 0.89 SPHK1 (0.36) CYP2C9SPHK1AOC3
SCHEMBL22277316 0.89 CYP2C9 (0.37) CYP2C9SPHK1
SCHEMBL22277634 0.87 CNR2 (0.36) CYP2C9SPHK1
SCHEMBL17154214 0.86 HTR2A (0.30)
SCHEMBL22277293 0.86 HTR2A (0.30)
SCHEMBL22277667 0.86 NAAA (0.32) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed