Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277637 | 0.91 | HPGD (0.41) | HPGDLMNAMAPTALOX15SMN1; SMN2 | |
| SCHEMBL22277328 | 0.90 | HPGD (0.39) | HPGDCYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL10020059 | 0.85 | HPGD (0.39) | HPGDLMNAALOX15SMN1; SMN2GLA | |
| SCHEMBL22277662 | 0.85 | HPGD (0.38) | HPGDLMNAALOX15SMN1; SMN2GLA | |
| SCHEMBL22277665 | 0.85 | HPGD (0.38) | HPGDLMNAALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10020041 | 0.84 | HPGD (0.39) | HPGDSMN1; SMN2GLAMEN1KMT2A | |
| SCHEMBL22277675 | 0.84 | KDM1A (0.34) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL7907306 | 0.81 | HPGD (0.44) | HPGDCYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL7907302 | 0.81 | HPGD (0.44) | HPGDCYP2C9LMNAALDH1A1MAPT | |
| SCHEMBL19985394 | 0.81 | ESR2 (0.34) | CYP2C9LMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |