Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277662 | 0.94 | HPGD (0.38) | HPGDLMNAALOX15FFAR4SMN1; SMN2 | |
| SCHEMBL22277622 | 0.90 | HPGD (0.37) | HPGDLMNAALOX15CCR5FFAR4 | |
| SCHEMBL22277608 | 0.89 | HPGD (0.38) | HPGDLMNAALOX15CCR5FFAR4 | |
| SCHEMBL22277313 | 0.87 | HPGD (0.39) | HPGDLMNAALOX15CCR5CYP3A4 | |
| SCHEMBL22277702 | 0.85 | HPGD (0.39) | HPGDLMNAALOX15SMN1; SMN2KMT2A | |
| SCHEMBL22277320 | 0.83 | HPGD (0.38) | HPGDLMNAALOX15FFAR4SMN1; SMN2 | |
| SCHEMBL22277637 | 0.82 | HPGD (0.41) | HPGDLMNAALOX15SMN1; SMN2KMT2A | |
| SCHEMBL22277664 | 0.80 | SPHK1 (0.45) | — | |
| SCHEMBL7745428 | 0.80 | ALDH1A1 (0.38) | HPGDFFAR4SMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL7745424 | 0.80 | ALDH1A1 (0.38) | HPGDFFAR4SMN1; SMN2ACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |