Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326231 | 0.82 | S1PR1 (0.39) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL22627225 | 0.79 | LMNA (0.46) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL27783817 | 0.78 | LMNA (0.43) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL162508 | 0.78 | LMNA (0.43) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL6776433 | 0.76 | LMNA (0.42) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL6776790 | 0.74 | PTGS1 (0.40) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL16669746 | 0.73 | LMNA (0.39) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL14741924 | 0.73 | LMNA (0.44) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL27971734 | 0.72 | LMNA (0.48) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL2601699 | 0.72 | PTGS1 (0.41) | LMNASLC6A6CYP2C19BLMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368003-A1 | COSMETIC COMPOSITION COMPRISING POLYURETHANE | Covestro Deutschland AG (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017070919-A1 | COSMETIC COMPOSITION COMPRISING POLYURETHANE | COVESTRO DEUTSCHLAND AG (DE) | 2017-05-04 | — | — | WO | disclosed |
| EP-2118161-B1 | POLYURETHANE DISPERSIONS BASED ON 2,2'-MDI | BAYER MATERIALSCIENCE AG (DE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011144530-A1 | PROCESS FOR JOINING TOGETHER COMPONENTS, IN PARTICULAR IN THE PRODUCTION OF SHOES | BAYER MATERIALSCIENCE AG (DE) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011089154-A2 | A PROCESS FOR THE PRODUCTION OF WATER-EMULSIFIABLE POLYURETHANE-POLYACRYLATE HYBRID SYSTEMS | BAYER MATERIALSCIENCE AG (DE) | 2011-07-28 | — | — | WO | disclosed |