SCHEMBL22277771

SCHEMBL22277771

CCCCCc1ccc(-c2ccc(C3CCC(CCc4ccc(OCCCC)c(F)c4F)CC3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.45
SPHK2 Q9NRA0 7/20 0.40
FFAR4 Q5NUL3 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277660 0.95 SPHK1 (0.46) SPHK1SPHK2FFAR4
SCHEMBL22277318 0.95 SPHK1 (0.38) SPHK1SPHK2FFAR4
SCHEMBL22277533 0.94 SPHK1 (0.45) SPHK1SPHK2FFAR4
SCHEMBL22277311 0.92 SPHK1 (0.40) SPHK1SPHK2FFAR4
SCHEMBL22277308 0.91 SPHK1 (0.38) SPHK1SPHK2FFAR4
SCHEMBL22277634 0.90 CNR2 (0.36) SPHK1SPHK2FFAR4
SCHEMBL22277740 0.89 SPHK1 (0.38) SPHK1SPHK2FFAR4
SCHEMBL22277309 0.89 SPHK1 (0.46) SPHK1SPHK2FFAR4
SCHEMBL22277772 0.89 FFAR4 (0.35) SPHK1SPHK2FFAR4
SCHEMBL22277767 0.88 SPHK1 (0.36) SPHK1SPHK2FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed