SCHEMBL22277772

SCHEMBL22277772

C/C=C/CCc1ccc(-c2ccc(C3CCC(CCc4ccc(OCCCC)c(F)c4F)CC3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.35
SPHK1 Q9NYA1 11/20 0.34
KCNH2 Q12809 2/20 0.33
S1PR1 P21453 1/20 0.31
SPHK2 Q9NRA0 7/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277666 0.95 SPHK1 (0.34) FFAR4SPHK1KCNH2SPHK2
SCHEMBL22277737 0.93 FFAR4 (0.34) FFAR4SPHK1KCNH2
SCHEMBL22277770 0.91 ALOX5 (0.34) SPHK1KCNH2
SCHEMBL22277634 0.90 CNR2 (0.36) FFAR4SPHK1S1PR1SPHK2
SCHEMBL22277318 0.90 SPHK1 (0.38) FFAR4SPHK1KCNH2S1PR1SPHK2
SCHEMBL22277771 0.89 SPHK1 (0.45) FFAR4SPHK1SPHK2
SCHEMBL22277775 0.89 SPHK1 (0.42) FFAR4SPHK1SPHK2
SCHEMBL22277671 0.88 SPHK1 (0.35) FFAR4SPHK1SPHK2
SCHEMBL22277652 0.88 SPHK1 (0.34) FFAR4SPHK1SPHK2
SCHEMBL22277621 0.87 AOC3 (0.32) FFAR4SPHK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed