Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CHKA | P35790 | 7/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228476 | 0.94 | MC4R (0.51) | KDM4EALDH1A1POLBCHKATNKS | |
| SCHEMBL20237949 | 0.89 | CYP19A1 (0.50) | KDM4EALDH1A1TNKSPARP1TNKS2 | |
| SCHEMBL2229998 | 0.86 | ALDH1A1 (0.53) | KDM4EALDH1A1POLBTNKSPARP1 | |
| SCHEMBL28024574 | 0.86 | COMT (0.53) | ALDH1A1TNKSPARP1TNKS2 | |
| SCHEMBL20804350 | 0.86 | COMT (0.53) | ALDH1A1TNKSPARP1TNKS2 | |
| SCHEMBL2229808 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1POLBTNKSPARP1 | |
| SCHEMBL519226 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1POLBTNKSPARP1 | |
| SCHEMBL20381979 | 0.81 | KMT2A (0.60) | ALDH1A1TNKSPARP1TNKS2CHRNA7 | |
| SCHEMBL20328137 | 0.81 | COMT (0.48) | ALDH1A1TNKSPARP1TNKS2 | |
| SCHEMBL16121610 | 0.81 | CHKA (0.53) | KDM4EALDH1A1POLBCHKATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469710-B2 | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20150148489-A1 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-05-28 | — | — | US | disclosed |
| US-20120296041-A1 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |