Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226083 | 0.72 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4052407 | 0.72 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26117231 | 0.68 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26117238 | 0.68 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1550552 | 0.67 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24691265 | 0.67 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25274712 | 0.67 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24108846 | 0.67 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25275132 | 0.67 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25275131 | 0.67 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091407-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLP (US) | 2011-07-28 | — | — | WO | disclosed |