Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.55 |
| ▸ | RORA | P35398 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278766 | 0.92 | RORC (0.65) | RORCNR1I2RORARORB | |
| SCHEMBL24061198 | 0.92 | RORC (0.58) | RORCNR1I2RORARORB | |
| SCHEMBL24061270 | 0.92 | RORC (0.58) | RORCNR1I2RORARORB | |
| SCHEMBL22278719 | 0.88 | RORC (0.64) | RORCNR1I2RORARORB | |
| SCHEMBL22278509 | 0.88 | RORC (0.60) | RORCNR1I2RORARORB | |
| SCHEMBL22278761 | 0.87 | RORC (0.67) | RORCNR1I2RORARORB | |
| SCHEMBL22278493 | 0.86 | RORC (0.61) | RORCNR1I2RORARORB | |
| SCHEMBL22278505 | 0.86 | RORC (0.61) | RORCNR1I2RORARORB | |
| SCHEMBL22278471 | 0.86 | RORC (0.68) | RORCNR1I2RORARORB | |
| SCHEMBL22278691 | 0.86 | RORC (0.68) | RORCNR1I2RORARORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151232-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2020-07-30 | — | — | WO | disclosed |