Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667256 | 0.90 | PRMT5 (0.49) | PRMT5WDR77PIK3CDMKNK1GPR119 | |
| SCHEMBL30207872 | 0.90 | PRMT5 (0.49) | PRMT5WDR77PIK3CDMKNK1GPR119 | |
| SCHEMBL19667108 | 0.82 | PRMT5 (0.45) | PRMT5MKNK1GPR119 | |
| SCHEMBL30207849 | 0.80 | GPR119 (0.37) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL19667549 | 0.80 | GPR119 (0.37) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL19667132 | 0.80 | GPR119 (0.39) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL30207976 | 0.80 | GPR119 (0.39) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL24109069 | 0.77 | PRMT5 (0.53) | PRMT5WDR77MKNK1GPR119MET | |
| SCHEMBL20911153 | 0.77 | PRMT5 (0.48) | PRMT5WDR77PIK3CDMKNK1GPR119 | |
| SCHEMBL30501364 | 0.77 | PRMT5 (0.68) | PRMT5WDR77MKNK1GPR119MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020152557-A1 | POLYMORPH FORM OF A MONOPHOSPHATE HYDRATE SALT OF A KNOWN TETRAHYDROISOQUINOLINE DERIVATIVE | PFIZER INC. (US) | 2020-07-30 | — | — | WO | disclosed |