SCHEMBL2228

SCHEMBL2228

[CH2]C#CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559456 0.72
Ethylene SCHEMBL4454205 0.67
SCHEMBL51760 0.63
SCHEMBL66494 0.63
SCHEMBL93566 0.58
SCHEMBL6157593 0.58
SCHEMBL2105710 0.54
SCHEMBL590694 0.54
SCHEMBL4597 0.53
SCHEMBL2575806 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718653-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY Ligand Pharmaceuticals Inc. (US) 2006-11-08 EP claimed
WO-2005082909-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-09 WO claimed
US-4381310-A Antimycotic substituted 2,4-dichlorophenyl-imidazolyl-vinyl-carbinols BAYER AKTIENGESELLSCHAFT (DE) 1983-04-26 US claimed
EP-0048828-A1 Substituted 2,4-dichlorophenyl-imidazolyl-vinyl carbinols, process for their preparation and antimicrobial agents containing these compounds BAYER AG (DE) 1982-04-07 EP claimed
EP-0048827-A1 Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds BAYER AG (DE) 1982-04-07 EP claimed
EP-0047016-A1 Progesterone derivatives, process for their production, and pharmaceutical compositions MERRELL DOW PHARMACEUTICALS INC. (US) 1982-03-10 EP claimed
WO-2024073349-A2 CLEAVABLE LINKERS FOR THE TETHERING OF POLYMERASES TO NUCLEOTIDES ANSA BIOTECHNOLOGIES, INC. (US) 2024-04-04 WO disclosed
WO-2020189540-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE 中外製薬株式会社 2020-09-24 WO disclosed
US-8133851-B2 Heteroaroyl-substituted serine amides BASF SE (DE) 2012-03-13 US disclosed
US-20110318470-A1 Method For Improving Plant Health BASF SE (DE) 2011-12-29 US disclosed
US-20110209253-A1 Method for Improving Plant Health BASF SE (DE) 2011-08-25 US disclosed
EP-2348841-A1 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2011-08-03 EP disclosed
EP-2348849-A1 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2011-08-03 EP disclosed
EP-0443983-A1 Acyl compounds CIBA-GEIGY AG (CH) 1991-08-28 EP disclosed
EP-0435827-A2 Diaza compounds CIBA-GEIGY AG (CH) 1991-07-03 EP disclosed
EP-0407342-A2 Pyrimidine derivatives CIBA-GEIGY AG (CH) 1991-01-09 EP disclosed
US-4435411-A Combating fungi with 1-phenyl-2-(1,2,4-triazol-1-yl)-prop-2-en-1-ones BAYER AKTIENGESELLSCHAFT (DE) 1984-03-06 US disclosed
US-4381310-A Antimycotic substituted 2,4-dichlorophenyl-imidazolyl-vinyl-carbinols BAYER AKTIENGESELLSCHAFT (DE) 1983-04-26 US disclosed
EP-0048828-A1 Substituted 2,4-dichlorophenyl-imidazolyl-vinyl carbinols, process for their preparation and antimicrobial agents containing these compounds BAYER AG (DE) 1982-04-07 EP disclosed
EP-0048827-A1 Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds BAYER AG (DE) 1982-04-07 EP disclosed