Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.77 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.76 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.76 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.76 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.76 |
| ▸ | GPR183 | P32249 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23847648 | 0.93 | S1PR1 (0.76) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL1876055 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL2193187 | 0.87 | S1PR1 (0.75) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL30948381 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL1413256 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL29560683 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL2195471 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL2195490 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL29691988 | 0.87 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Ozanimod SCHEMBL20569961 | 0.86 | S1PR1 (0.98) | S1PR1S1PR4S1PR3S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020152718-A1 | POLYMORPHIC FORMS 5-[3-[(1S)-2,3-DIHYDRO-1-[(2-HYDROXYETHYL) AMINO]-1H-INDEN-4-YL]-1,2,4-OXADIAZOL-5-YL]-2-(1-METHYLETHOXY)BENZONITRILE | MYLAN LABORATORIES LIMITED (IN) | 2020-07-30 | — | — | WO | disclosed |