SCHEMBL2228056

SCHEMBL2228056

Cc1cc(N)nc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29975293 1.00
SCHEMBL105871 0.81
SCHEMBL1821173 0.81
SCHEMBL14141855 0.75
SCHEMBL2087998 0.75 HTR6 (0.33)
SCHEMBL94111 0.74
SCHEMBL31324837 0.74
SCHEMBL927252 0.74
SCHEMBL29524640 0.74
SCHEMBL16506708 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109714-A1 PYRIMIDINE-FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-04-23 US disclosed
US-12570671-B2 Substituted oxoisoindoline compounds for the treatment of cancer BRISTOL-MYERS SQUIBB COMPANY (US) 2026-03-10 US disclosed
EP-4126843-B1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP disclosed
US-12459932-B2 KIF18A inhibitors AMGEN INC. (US) 2025-11-04 US disclosed
EP-4615839-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE Bristol-Myers Squibb Company (US) 2025-09-17 EP disclosed
EP-4606803-A1 KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) 2025-08-27 EP disclosed
US-20250263424-A1 KRAS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2025-08-21 US disclosed
EP-4592295-A1 PYRIMIDINE-FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2025-07-30 EP disclosed
EP-4568952-A1 KRAS INHIBITORS Bristol-Myers Squibb Company (US) 2025-06-18 EP disclosed
CN-120152973-A Protein tyrosine phosphatase inhibitors, compositions, and methods of use 百时美施贵宝公司 2025-06-13 CN disclosed
EP-0690846-A1 HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-01-10 EP disclosed
EP-0665841-A1 HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES. SHELL INT RESEARCH (NL) 1995-08-09 EP disclosed
US-5374604-A 2,6-diphenoxypyridine as pre-emergence herbicides AMERICAN CYANAMID COMPANY (US) 1994-12-20 US disclosed
WO-1994022833-A1 HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-10-13 WO disclosed
CN-1086516-A Herbicidal picolinamide derivatives SHELL INT RESEARCH (NL) 1994-05-11 CN disclosed
WO-1994008991-A1 HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-04-28 WO disclosed
CN-1079220-A 2, 6-substituted pyridine herbicides SHELL INT RESEARCH (NL) 1993-12-08 CN disclosed
EP-0572093-A1 Herbicidal 2,6-substituted pyridines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-12-01 EP disclosed
US-4372778-A Herbicidal N-(pyridinylaminocarbonyl)benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-08 US disclosed
US-4293330-A Herbicidal N-(pyridinylaminocarbonyl)benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-06 US disclosed