Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280721 | 0.95 | PIK3CG (0.40) | PIK3CGPIK3CDNTRK1PRKDCNPC1 | |
| SCHEMBL22280626 | 0.91 | PIK3CG (0.38) | PIK3CGPIK3CDNPC1CYP1A2CYP2D6 | |
| SCHEMBL22280415 | 0.87 | PIK3CG (0.40) | PIK3CGPIK3CDNPC1CYP1A2CYP2D6 | |
| SCHEMBL22276817 | 0.87 | PIK3CG (0.37) | PIK3CGPIK3CDNTRK1PRKDCNPC1 | |
| SCHEMBL22265212 | 0.80 | PIK3CG (0.36) | PIK3CGPIK3CDNPC1CYP1A2CYP2D6 | |
| SCHEMBL22280418 | 0.76 | RAD52 (0.39) | PIK3CGPIK3CD | |
| SCHEMBL22280729 | 0.76 | PIK3CG (0.41) | PIK3CGPIK3CDNTRK1PRKDCNPC1 | |
| SCHEMBL24061311 | 0.75 | PIK3CG (0.37) | PIK3CGPIK3CDNPC1CYP1A2CYP2C19 | |
| SCHEMBL22276799 | 0.74 | PIK3CG (0.37) | PIK3CGPIK3CDNPC1CYP1A2CYP2C19 | |
| SCHEMBL22280613 | 0.74 | RAB9A (0.40) | PIK3CGPIK3CDNPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |