⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055584 | 0.64 | INMT (0.32) | — | |
| SCHEMBL1177147 | 0.61 | — | — | |
| SCHEMBL3043 | 0.61 | — | — | |
| SCHEMBL13265156 | 0.61 | INMT (0.30) | — | |
| SCHEMBL9945748 | 0.61 | — | — | |
| SCHEMBL8644481 | 0.61 | — | — | |
| SCHEMBL2398125 | 0.61 | BRD4 (0.43) | — | |
| SCHEMBL13238885 | 0.61 | INMT (0.30) | — | |
| SCHEMBL717518 | 0.61 | BRD4 (0.43) | — | |
| Fluoride SCHEMBL6368967 | 0.59 | BRD4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124607-A1 | 5-Substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists | ROCHE PALO ALTO LLC | 2005-06-09 | — | — | US | claimed |
| US-20140030182-A1 | CARBON FILMS PRODUCED FROM IONIC LIQUID CARBON PRECURSORS | UT-BATTELLE, LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-8574534-B2 | Carbon films produced from ionic liquid carbon precursors | UT-BATTELLE, LLC (US) | 2013-11-05 | — | — | US | disclosed |
| US-8524388-B2 | Superbase-derived protic ionic liquids | UT-BATTELLE, LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-20110229401-A1 | Carbon Films Produced from Ionic Liquid Carbon Precursors | UT-BATTELLE, LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110177428-A1 | Superbase-Derived Protic Ionic Liquids | UT-BATTELLE, LLC (US) | 2011-07-21 | — | — | US | disclosed |
| EP-1644343-B1 | 5-SUBSTITUTED QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | EP | disclosed |
| EP-1644343-A1 | 5-SUBSTITUTED QUINAZOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| US-20050124607-A1 | 5-Substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists | ROCHE PALO ALTO LLC | 2005-06-09 | — | — | US | disclosed |
| WO-2005005397-A1 | 5-SUBSTITUTED QUINAZOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-20 | — | — | WO | disclosed |