⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689034 | 0.83 | OR51E2 (0.39) | — | |
| SCHEMBL8866832 | 0.70 | OR51E2 (0.47) | — | |
| SCHEMBL8866835 | 0.65 | OR51E2 (0.43) | — | |
| SCHEMBL634528 | 0.65 | OR51E2 (0.33) | — | |
| SCHEMBL29425335 | 0.65 | — | — | |
| SCHEMBL16738070 | 0.62 | OR51E2 (0.37) | — | |
| SCHEMBL11720970 | 0.61 | CRBN (0.50) | — | |
| SCHEMBL5056719 | 0.61 | OR51E2 (0.39) | — | |
| SCHEMBL22908210 | 0.61 | — | — | |
| SCHEMBL22908208 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583958-A | Synthesis method of dihydrothia (oxa) zole [3',2':1,5] dihydroimidazole [4,5-b ] piperidine derivative | 河南师范大学 | 2023-01-10 | — | — | CN | claimed |
| CN-115583958-A | Synthesis method of dihydrothia (oxa) zole [3',2':1,5] dihydroimidazole [4,5-b ] piperidine derivative | 河南师范大学 | 2023-01-10 | — | — | CN | disclosed |
| EP-2647647-A2 | Thiopeptide precursor protein, gene encoding it and uses thereof | Novartis AG (CH) | 2013-10-09 | — | — | EP | disclosed |
| US-20110183374-A1 | THIOPEPTIDE PRECURSOR PROTEIN, GENE ENCODING IT AND USES THEREOF | NOVARTIS AG | 2011-07-28 | — | — | US | disclosed |
| EP-2178907-A1 | THIOPEPTIDE PRECURSOR PROTEIN, GENE ENCODING IT AND USES THEREOF | Novartis Ag (CH) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009019289-A1 | THIOPEPTIDE PRECURSOR PROTEIN, GENE ENCODING IT AND USES THEREOF | NOVARTIS AG (CH) | 2009-02-12 | — | — | WO | disclosed |