Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908208 | 0.85 | — | — | |
| SCHEMBL13812990 | 0.79 | — | — | |
| SCHEMBL23794186 | 0.75 | OR51E2 (0.46) | OR51E2CRBNFKBP5 | |
| SCHEMBL16738070 | 0.70 | OR51E2 (0.37) | OR51E2CRBNFKBP5 | |
| SCHEMBL5056719 | 0.69 | OR51E2 (0.39) | OR51E2CRBNFKBP5 | |
| SCHEMBL20100268 | 0.69 | — | — | |
| SCHEMBL19689034 | 0.69 | OR51E2 (0.39) | OR51E2CRBNFKBP5UHRF1 | |
| SCHEMBL2228088 | 0.65 | — | — | |
| SCHEMBL8866832 | 0.65 | OR51E2 (0.47) | OR51E2CRBNFKBP5UHRF1 | |
| SCHEMBL24497344 | 0.64 | OR51E2 (0.35) | OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700941-A | Octahydronaphthyridine derivatives | MERCK, SHARP & DOHME, LTD. (GB) | 1997-12-23 | — | — | US | disclosed |