Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723979 | 0.81 | LMNA (0.39) | BLMKMT2ATSHRALDH1A1PKM | |
| SCHEMBL31723955 | 0.75 | LMNA (0.40) | BLMKMT2AALOX15PMP22TSHR | |
| SCHEMBL31723991 | 0.75 | LMNA (0.44) | KMT2ATSHRALDH1A1PKMMEN1 | |
| SCHEMBL21820033 | 0.73 | LMNA (0.41) | BLMKMT2AALOX15PMP22TSHR | |
| SCHEMBL11063885 | 0.71 | CHRM2 (0.33) | ALDH1A1PKMLMNACHRM2CHRM4 | |
| SCHEMBL6565960 | 0.70 | HDAC3 (0.40) | KMT2ATSHRALDH1A1PKMMEN1 | |
| SCHEMBL6141655 | 0.69 | LMNA (0.34) | KMT2ATSHRMEN1LMNACA12 | |
| SCHEMBL31723967 | 0.69 | LMNA (0.45) | BLMKMT2ATSHRALDH1A1PKM | |
| SCHEMBL8763346 | 0.68 | SMN1; SMN2 (0.53) | KMT2ATSHRALDH1A1PKMMEN1 | |
| SCHEMBL23618003 | 0.67 | MAPT (0.46) | KMT2ATSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523982-B1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | CIS PHARMA AG (CH) | 2015-04-29 | — | — | EP | disclosed |
| US-8980957-B2 | Methods for the preparation of biocompatible polymers, the polymers and their uses | CIS PHARMA AG (CH) | 2015-03-17 | — | — | US | disclosed |
| US-20120329902-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | SCHAEFER ROLF (CH) | 2012-12-27 | — | — | US | disclosed |
| EP-2523982-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | Chemisches Institut Schaefer AG (CH) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011085988-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2011-07-21 | — | — | WO | disclosed |