SCHEMBL22282134

SCHEMBL22282134

c1ccc(-c2ccc3ccc4ccc(-c5ccc(-c6ccc7ccc(-c8ccc9ccc(-c%10ccccn%10)nc9c8)cc7n6)cc5)nc4c3n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 4/20 0.43
KDM4E B2RXH2 4/20 0.43
LMNA P02545 3/20 0.43
TP53 P04637 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPK1 P28482 2/20 0.43
CCR1 P32246 2/20 0.43
CCR5 P51681 2/20 0.43
CCR8 P51685 2/20 0.43
ALOX15 P16050 2/20 0.43
HTT P42858 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALPL P05186 1/20 0.43
HSP90AA1 P07900 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
IGF1R P08069 2/20 0.43
DHODH Q02127 1/20 0.43
NPC1 O15118 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22281845 1.00 TOP1 (0.43) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22970166 0.99 TOP1 (0.42) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22970524 0.97 IGF1R (0.41) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22970530 0.97 TOP1 (0.43) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL24454311 0.96 IGF1R (0.41) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22970534 0.96 KDM4E (0.44) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22282016 0.96 KDM4E (0.44) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22282119 0.95 MAOA (0.41) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL24475650 0.95 MAOA (0.41) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL22281912 0.94 KDM4E (0.48) TOP1KDM4ELMNATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE LT MATERIALS CO., LTD. (KR) 2022-06-02 US disclosed
WO-2020153740-A1 COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 엘티소재주식회사 2020-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 TOP1 3936/4885KDM4E 3814/4885LMNA 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.