Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.36 |
| ▸ | ABL1 | P00519 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 8/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599626 | 1.00 | SRC (0.36) | SRCABL1ALDH1A1NT5ECYP1A2 | |
| SCHEMBL24672311 | 0.86 | NT5E (0.45) | NT5E | |
| SCHEMBL28591366 | 0.85 | NT5E (0.44) | NT5E | |
| SCHEMBL28610588 | 0.85 | SRC (0.39) | SRCABL1ALDH1A1NT5ECYP1A2 | |
| SCHEMBL22281833 | 0.84 | NT5E (0.40) | SRCABL1NT5E | |
| SCHEMBL22281986 | 0.84 | NT5E (0.40) | SRCABL1NT5E | |
| SCHEMBL28610663 | 0.83 | NT5E (0.45) | NT5EPDE2A | |
| SCHEMBL28610664 | 0.83 | NT5E (0.45) | NT5EPDE2A | |
| SCHEMBL28610592 | 0.80 | NT5E (0.36) | NT5E | |
| SCHEMBL28600138 | 0.74 | NT5E (0.48) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151707-A1 | NOVEL SMALL MOLECULE CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-07-30 | — | — | WO | disclosed |