Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 17/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610664 | 1.00 | NT5E (0.45) | NT5EPDE2AKDRPDE9A | |
| SCHEMBL28918241 | 0.86 | NT5E (0.47) | NT5EPDE2AKDRPDE9A | |
| SCHEMBL28918240 | 0.86 | NT5E (0.47) | NT5EPDE2AKDRPDE9A | |
| SCHEMBL22281832 | 0.85 | NT5E (0.46) | NT5EPDE2A | |
| SCHEMBL28595914 | 0.85 | NT5E (0.46) | NT5EPDE2A | |
| SCHEMBL28599626 | 0.83 | SRC (0.36) | NT5EPDE2A | |
| SCHEMBL22282192 | 0.83 | SRC (0.36) | NT5EPDE2A | |
| SCHEMBL24672311 | 0.82 | NT5E (0.45) | NT5E | |
| SCHEMBL28591366 | 0.81 | NT5E (0.44) | NT5E | |
| SCHEMBL28610592 | 0.81 | NT5E (0.36) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955444-A | Novel small-molecule CD73 inhibitor, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2021-06-11 | — | — | CN | disclosed |