Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17191610 | 0.89 | PIK3CD (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PIK3CD | |
| SCHEMBL29879121 | 0.82 | BLM (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4BLM | |
| SCHEMBL25509703 | 0.79 | TSHR (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4HDAC1 | |
| SCHEMBL22151616 | 0.79 | BLM (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BLM | |
| SCHEMBL19002259 | 0.79 | BLM (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BLM | |
| SCHEMBL23217972 | 0.76 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4BLM | |
| SCHEMBL22957198 | 0.76 | PDK2 (0.37) | BLMPMP22HSD17B10HDAC1HDAC6 | |
| SCHEMBL21900626 | 0.76 | PIK3CD (0.36) | BLMPMP22HSD17B10PIK3CDMEN1 | |
| SCHEMBL5826298 | 0.76 | BLM (0.38) | BLMPMP22HSD17B10TSHR | |
| SCHEMBL5826288 | 0.76 | BLM (0.38) | BLMPMP22HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154447-A1 | MTORC MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |