Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | EP300 | Q09472 | 3/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276978 | 0.73 | KDM4E (0.57) | IDO1MAPTHPGDAPPALOX15 | |
| SCHEMBL28919623 | 0.70 | — | — | |
| SCHEMBL29846477 | 0.69 | CDC25B (0.30) | — | |
| SCHEMBL30574445 | 0.69 | CDC25B (0.30) | — | |
| SCHEMBL29507259 | 0.67 | IDO1 (0.56) | IDO1EP300KAT2BKAT8MAPT | |
| SCHEMBL11281349 | 0.67 | IDO1 (0.56) | IDO1EP300KAT2BKAT8MAPT | |
| SCHEMBL22295161 | 0.66 | HSD17B10 (0.39) | IDO1MAPTHPGDALOX15RECQL | |
| SCHEMBL29362983 | 0.65 | IDO1 (1.00) | IDO1EP300KAT2BKAT8MAPT | |
| SCHEMBL29638 | 0.65 | IDO1 (1.00) | IDO1EP300KAT2BKAT8MAPT | |
| SCHEMBL32677325 | 0.65 | IDO1 (1.00) | IDO1EP300KAT2BKAT8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691011-A1 | DIHYDROXYPHTHALAZINES, THEIR PRODUCTION AND USE | Justus-Liebig-Universität Gießen (DE) | 2020-08-05 | — | — | EP | disclosed |
| EP-3691011-A1 | DIHYDROXYPHTHALAZINES, THEIR PRODUCTION AND USE | Justus-Liebig-Universität Gießen (DE) | 2020-08-05 | — | — | EP | disclosed |