SCHEMBL276978

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22283932	0.73	IDO1 (0.47)	KDM4EMAPKAPK2CYP1A2IDO1MAPT
	SCHEMBL276528	0.73	KDM4E (0.70)	KDM4EMAPKAPK2CYP1A2IDO1TDO2
	SCHEMBL29547804	0.73	KDM4E (0.70)	KDM4EMAPKAPK2CYP1A2IDO1TDO2
	SCHEMBL276518	0.73	KDM4E (1.00)	KDM4EMAPKAPK2CYP1A2PLAUCTDSP1
	SCHEMBL6122152	0.71	MAPT (0.38)	KDM4EMAPKAPK2CYP1A2MAPTTDP1
	SCHEMBL19595854	0.71	PSMD14 (0.40)	KDM4EMAPKAPK2CYP1A2MAPTTDP1
	SCHEMBL659473	0.71	NOS1 (0.42)	KDM4EMAPKAPK2CYP1A2MAPTTDP1
	SCHEMBL659324	0.71	CYP3A4 (0.57)	KDM4ECYP1A2PLAUMAPTTSHR
	SCHEMBL5364164	0.71	ALDH1A1 (0.52)	KDM4ECYP1A2MAPTTSHRHPGD
	SCHEMBL19001494	0.71	NOS1 (0.42)	KDM4EMAPKAPK2CYP1A2MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.