Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181613 | 0.99 | DPP8 (0.61) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL2033858 | 0.99 | DPP8 (0.61) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL2032072 | 0.99 | DPP8 (0.61) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL6375258 | 0.95 | HTT (0.62) | DPP8DPP7TGM2HTTANPEP | |
| Hydrochloric Acid SCHEMBL6374328 | 0.94 | HTT (0.60) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL27784040 | 0.89 | DPP8 (0.59) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL1586919 | 0.88 | DPP8 (0.61) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL1586916 | 0.88 | DPP8 (0.61) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL28841677 | 0.88 | DPP8 (0.58) | DPP8DPP7TGM2HTTANPEP | |
| SCHEMBL2424896 | 0.88 | HTT (0.71) | DPP8DPP7TGM2HTTANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809686-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | Cerulean Pharma Inc. (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116200-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| WO-2013025490-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASES | CERULEAN PHARMA INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| WO-2011090940-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2011-07-28 | — | — | WO | disclosed |