Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL22284789 | 0.87 | TSHR (0.37) | CYP2D6CYP2C19KMT2ALMNAGAA | |
| SCHEMBL309217 | 0.82 | CYP2D6 (0.47) | CYP2D6CYP2C19 | |
| SCHEMBL22284790 | 0.78 | TSHR (0.37) | CYP2D6KMT2ALMNANPC1RAB9A | |
| SCHEMBL29392902 | 0.72 | IDO1 (0.30) | CYP2D6CYP2C19 | |
| Benzoic Acid SCHEMBL1033231 | 0.67 | CA2 (0.76) | CA2CA4LMNASMN1; SMN2TSHR | |
| SCHEMBL29016421 | 0.67 | KMT2A (0.50) | CYP2D6CYP2C19KMT2ALMNAGAA | |
| Benzoic Acid SCHEMBL31683096 | 0.66 | CA2 (0.61) | CA2CA4KMT2ALMNANPC1 | |
| SCHEMBL28743235 | 0.66 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| Benzoic Acid SCHEMBL27345977 | 0.65 | CA2 (0.90) | CA2CA4TSHRCA1ALDH1A1 | |
| Benzoic Acid SCHEMBL431405 | 0.65 | CA2 (1.00) | CA2CA4CYP2C19HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560490-B2 | Water-based ink composition for ballpoint pen and water-based ballpoint pen using the same | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2023-01-24 | — | — | US | disclosed |
| CN-111263796-B | Ink composition for water-based ballpoint pen and water-based ballpoint pen using the same | 株式会社百乐 | 2022-12-06 | — | — | CN | disclosed |
| EP-3702420-A1 | INK COMPOSITION FOR WATER-BASED BALLPOINT PEN, AND WATER-BASED BALLPOINT PEN INCLUDING SAME | Kabushiki Kaisha Pilot Corporation (also trading as Pilot Corporation) (JP) | 2020-09-02 | — | — | EP | disclosed |
| US-20200248019-A1 | WATER-BASED INK COMPOSITION FOR BALLPOINT PEN AND WATER-BASED BALLPOINT PEN USING THE SAME | KABUSHIKI KAISHA PILOT CORPORATION (ALSO TRADING AS PILOT CORPORATION) (JP) | 2020-08-06 | — | — | US | disclosed |
| CN-111263796-A | Ink composition for water-based ballpoint pen and water-based ballpoint pen using the same | 株式会社百乐 | 2020-06-09 | — | — | CN | disclosed |