Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230074 | 0.90 | BRD4 (0.39) | BRD4MAPTHTTP2RX7SIGMAR1 | |
| SCHEMBL5202907 | 0.86 | MAPT (0.47) | MAPTKDM4EGAAHTTP2RX7 | |
| SCHEMBL2227867 | 0.80 | BRD4 (0.43) | BRD4MAPTKDM4EGAARORC | |
| SCHEMBL25011488 | 0.80 | BRD4 (0.41) | BRD4MAPTKDM4EGAARORC | |
| SCHEMBL21392344 | 0.78 | KDM4E (0.58) | MAPTKDM4EGAAP2RX7SIGMAR1 | |
| SCHEMBL7634561 | 0.77 | GAA (0.61) | MAPTKDM4EGAAP2RX7SIGMAR1 | |
| SCHEMBL23016004 | 0.77 | GAA (0.61) | MAPTKDM4EGAAP2RX7SIGMAR1 | |
| SCHEMBL13246644 | 0.74 | MAPK1 (0.46) | BRD4MAPTKDM4EGAAHTT | |
| SCHEMBL2087914 | 0.74 | MAPT (0.41) | MAPTKDM4EGAAHTTP2RX7 | |
| SCHEMBL82901 | 0.74 | BRD4 (0.54) | BRD4MAPTKDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |