SCHEMBL21392344

SCHEMBL21392344

Cc1ccccc1NC1CCCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.58
MAPT P10636 2/20 0.58
GAA P10253 2/20 0.58
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
HDAC8 Q9BY41 1/20 0.47
SIGMAR1 Q99720 3/20 0.47
P2RX7 Q99572 2/20 0.47
IDO1 P14902 1/20 0.47
ALOX12 P18054 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7634561 0.98 GAA (0.61) KDM4EMAPTGAALMNASMN1; SMN2
SCHEMBL23016004 0.98 GAA (0.61) KDM4EMAPTGAALMNASMN1; SMN2
SCHEMBL5202907 0.91 MAPT (0.47) KDM4EMAPTGAALMNASMN1; SMN2
Bicarbonate SCHEMBL11086979 0.89 P2RX7 (0.55) KDM4EMAPTGAASMN1; SMN2HDAC8
SCHEMBL6255267 0.87 BRD4 (0.48) KDM4EMAPTGAALMNASMN1; SMN2
SCHEMBL11521138 0.84 KDM4E (0.69) KDM4EMAPTGAALMNASMN1; SMN2
SCHEMBL27228563 0.83 LMNA (0.48) KDM4EMAPTGAALMNASMN1; SMN2
SCHEMBL13246644 0.82 MAPK1 (0.46) KDM4EMAPTGAAALDH1A1NPC1
SCHEMBL2087914 0.82 MAPT (0.41) KDM4EMAPTGAALMNAALDH1A1
SCHEMBL82901 0.82 BRD4 (0.54) KDM4EMAPTGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10886477-B2 Iridium complex and organic electroluminescence device using the same UDC IRELAND LIMITED (IE) 2021-01-05 US disclosed
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IMPA1, LAGE3, OCIAD1 KDM4E 3501/4885MAPT 909/4885GAA 2328/4885
US-10886477-B2 Iridium complex and organic electroluminescence device using the same IMPA1, LAGE3, OCIAD1 KDM4E 3501/4885MAPT 909/4885GAA 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.