SCHEMBL2228829

SCHEMBL2228829

CC1(O)CCCC(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482646 0.91 TRIM24 (0.42)
SCHEMBL22930634 0.85
SCHEMBL14265648 0.85
SCHEMBL6280761 0.81 LMNA (0.34)
SCHEMBL6280755 0.81 LMNA (0.34)
SCHEMBL6280752 0.81 LMNA (0.34)
SCHEMBL8749 0.75
SCHEMBL20797183 0.73
SCHEMBL23531315 0.71
SCHEMBL11427690 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10414918-B2 Method of preparing polymer compound TOKYO OHKA KOGYO CO., LTD. (JP) 2019-09-17 US disclosed
US-20180022916-A1 METHOD OF PREPARING POLYMER COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2018-01-25 US disclosed
US-20130123508-A1 NOVEL NONLINEAR CHROMOPHORES ESPECIALLY SUITED FOR USE IN ELECTRO-OPTICAL MODULATION ECOLE NORMALE SUPERIEURE DE LYON (FR) 2013-05-16 US disclosed
WO-2011089351-A1 NOVEL NONLINEAR CHROMOPHORES ESPECIALLY SUITED FOR USE IN ELECTRO-OPTICAL MODULATION ECOLE NORMALE SUPERIEURE DE LYON (FR) 2011-07-28 WO disclosed
WO-2010017046-A1 PYRAZOLO[1,5-A]PYRIDINES AS MARK INHIBITORS MERCK & CO., INC. (US) 2010-02-11 WO disclosed
EP-1038018-A4 ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES SCRIPPS RESEARCH INST (US) 2004-10-13 EP disclosed
US-6589766-B1 Use to catalyze ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products THE SCRIPPS RESEARCH INSTITUTE 2003-07-08 US disclosed
US-6326176-B1 ALDOL CONDENSATIONS AND CATALYTIC ANTIBODIES THE SCRIPPS RESEARCH INSTITUTE 2001-12-04 US disclosed
EP-1038018-A1 ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES The Scripps Research Institute (US) 2000-09-27 EP disclosed
WO-1999031263-A1 ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES THE SCRIPPS RESEARCH INSTITUTE (US) 1999-06-24 WO disclosed