Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.67 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288963 | 0.88 | PDE3B (0.62) | PDE3BPDE3AMAOB | |
| SCHEMBL22288678 | 0.86 | MAOB (0.56) | PDE3BPDE3AMAOB | |
| SCHEMBL22304511 | 0.82 | PDE3B (0.61) | PDE3BPDE3AMAOB | |
| SCHEMBL30692565 | 0.81 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL20705307 | 0.81 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL22288402 | 0.79 | PDE3B (0.61) | PDE3BPDE3AMAOB | |
| SCHEMBL22304856 | 0.79 | PDE3B (0.51) | PDE3BPDE3AMAOB | |
| SCHEMBL22288965 | 0.77 | MAOB (0.56) | PDE3BPDE3AMAOB | |
| SCHEMBL22304672 | 0.77 | PDE3B (0.66) | PDE3BPDE3AMAOB | |
| SCHEMBL22304508 | 0.77 | PDE3B (0.65) | PDE3BPDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |