Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16766049 | 0.94 | CA1 (0.33) | CA1CA2CA4 | |
| SCHEMBL25225527 | 0.86 | CA1 (0.35) | CA1CA2CA4 | |
| SCHEMBL1325803 | 0.83 | — | — | |
| SCHEMBL25277094 | 0.83 | CYP1A2 (0.35) | CA1CA2CA4CYP1A2 | |
| SCHEMBL16766406 | 0.82 | TDP1 (0.44) | CYP1A2 | |
| Water SCHEMBL28036465 | 0.82 | — | — | |
| SCHEMBL11880815 | 0.82 | CYP2C19 (0.31) | — | |
| SCHEMBL16765852 | 0.81 | TDP1 (0.40) | CYP1A2 | |
| SCHEMBL30621996 | 0.80 | TRPA1 (0.31) | — | |
| SCHEMBL16766423 | 0.79 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917510-A1 | TRANSIENT RECEPTOR POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS | Marshall University Research Corporation (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160464-A1 | TRANSIENT RECEPTOR POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS | MARSHALL UNIVERSITY RESEARCH CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |
| CN-101087772-A | High-purity alicyclic diepoxy compound and preparation method thereof | DAICEL CHEM (JP) | 2007-12-12 | — | — | CN | disclosed |