SCHEMBL22289873

SCHEMBL22289873

[CH2]C(C)N1C(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.41
GSK3A P49840 1/20 0.41
GSK3B P49841 1/20 0.41
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
THPO P40225 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FAAH O00519 3/20 0.34
HSP90AA1 P07900 1/20 0.31
CCR6 P51684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017 0.77 MGLL (0.45) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL43978 0.77 MGLL (0.45) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL13968985 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL969752 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL27421027 0.72 MGLL (0.38) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL2832318 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL8169087 0.72 MGLL (0.35) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL13742892 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL331187 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL19546122 0.72 MGLL (0.41) MGLLGSK3AGSK3BGMNNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917575-A1 PHLIP®-MEDIATED CARBOHYDRATE TETHERING AT CELL SURFACES TO INDUCE IMMUNE RESPONSE University of Rhode Island Board of Trustees (US) 2021-12-08 EP disclosed
WO-2020160031-A1 PHLIP®-MEDIATED CARBOHYDRATE TETHERING AT CELL SURFACES TO INDUCE IMMUNE RESPONSE RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) 2020-08-06 WO disclosed
CN-1272361-C photosensitive resin, resin composition and cured product thereof NIPPON KAYAKU KK (JP) 2006-08-30 CN disclosed
CN-1639227-A Photosensitive resins, resin compositions and products of curing thereof NIPPON KAYAKU KK (JP) 2005-07-13 CN disclosed