Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221800 | 1.00 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL29776615 | 1.00 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL10299795 | 1.00 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL222901 | 1.00 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL221801 | 1.00 | MDM2 (1.00) | MDM2TP53 | |
| SCHEMBL29776561 | 0.95 | MDM2 (0.90) | MDM2TP53 | |
| SCHEMBL222465 | 0.95 | MDM2 (0.90) | MDM2TP53 | |
| SCHEMBL1956570 | 0.95 | MDM2 (0.90) | MDM2TP53 | |
| SCHEMBL222469 | 0.95 | MDM2 (0.90) | MDM2TP53 | |
| SCHEMBL10299791 | 0.95 | MDM2 (0.90) | MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088815-B2 | Spiroindolinone pyrrolidines | HOFFMAN-LA ROCHE INC. (US) | 2012-01-03 | — | — | US | disclosed |