Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822370 | 0.84 | CYP3A4 (0.63) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL2231455 | 0.78 | KDM4E (0.68) | MAPTKDM4ECYP3A4LMNAHTT | |
| SCHEMBL27999878 | 0.78 | NR4A2 (0.59) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL4326486 | 0.76 | MET (0.49) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL217044 | 0.76 | MAPT (1.00) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL10416445 | 0.75 | MET (0.57) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL25195755 | 0.74 | KDM4E (0.61) | MAPTKDM4ECYP3A4LMNAHTT | |
| SCHEMBL12731938 | 0.74 | MAPT (0.61) | MAPTKDM4ECYP3A4LMNAHTT | |
| Hydrochloric Acid SCHEMBL28420480 | 0.73 | MAPT (0.94) | MAPTKDM4ENR4A2CYP3A4LMNA | |
| SCHEMBL2208273 | 0.73 | KDM4E (0.62) | MAPTKDM4ENR4A2HTTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |